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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396513Generated: October 24, 2026

1-(3-(Benzyloxy)phenyl)-2-bromoethanone → Methyl[6-chloro-2-(3-benzyloxybenzoyl)-1h-indol-3-yl]acetate

https://huagongshe.com/en/reaction/396513

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-(Benzyloxy)phenyl)-2-bromoethanoneHCID 88031—
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
ProductMethyl[6-chloro-2-(3-benzyloxybenzoyl)-1h-indol-3-yl]acetateHCID 23003368—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans 4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 3-benzyloxyphenacyl bromide (A. Hernandez et al., J. Org. Chem., 1994, 59, 1058).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-588122d7a8214075a94e8c6b6134a670
Source noteuspto-grants-2003_08