2-Bromo-1-(3-bromophenyl)ethan-1-one → Methyl[6-chloro-2-(3-bromobenzoyl)-1h-indol-3-yl]acetate

HRID 396529

Reaction equation

HRID 396529 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.[Br:24][C:25]1[CH:26]=[C:27]([CH:32]=[CH:33][CH:34]=1)[C:28](=[O:31])[CH2:29]Br>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:29]=1[C:28](=[O:31])[C:27]1[CH:32]=[CH:33][CH:34]=[C:25]([Br:24])[CH:26]=1

Participants

3

Reactant 2

HCID 5195852-Bromo-1-(3-bromophenyl)ethan-1-oneHCID 11371593Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate

Product 1

HCID 23003560Methyl[6-chloro-2-(3-bromobenzoyl)-1h-indol-3-yl]acetate

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans 4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 3-bromophenacyl bromide.

Sources & evidence

ORD record
ord-3c4c65ba7d834c9ea9f0d9323257fbc4
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Linked notes

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