N-BOC-ethylenediamine → [5-Chloro-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]-N-(2-aminoethyl)acetamide
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([C:13]1[CH:18]=[C:17]([CH3:19])[CH:16]=[CH:15][N:14]=1)=[O:12])=[C:5]2[CH2:20][C:21](O)=[O:22].C(OC(=O)[NH:30][CH2:31][CH2:32][NH2:33])(C)(C)C>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([C:13]1[CH:18]=[C:17]([CH3:19])[CH:16]=[CH:15][N:14]=1)=[O:12])=[C:5]2[CH2:20][C:21]([NH:30][CH2:31][CH2:32][NH2:33])=[O:22]Participants
3
Procedure
The title compound was prepared according to the procedure described in Example 43 from [5-chloro-2-(4-methylpyridine)-1H-indol-3-yl]acetic acid (Example 36) and N-(2-aminoethyl)carbamic acid tert-butyl ester.
Sources & evidence
- ORD record
- ord-9ab6fc4241e943849f12baeea2dde5f6
- Source dataset
- uspto-grants-2003_08