1,3-Dioxolane, 2-(bromomethyl)- → Methylnaphthylmethyl-[1,3]-dioxolan-2-ylmethylamine
Reaction equation
Cl.[CH3:2][NH:3][CH2:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1.[CH2:15]1[O:21][CH:18]([CH2:19]Br)[O:17][CH2:16]1>>[CH3:2][N:3]([CH2:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1)[CH2:19][CH:18]1[O:21][CH2:15][CH2:16][O:17]1Participants
3
Procedure
In a similar manner, the reaction of N-methyl-1-naphthalenemethylamine hydrochloride with bromoacetaldehyde ethylene acetal gives methylnaphthylmethyl-[1,3]-dioxolan-2-ylmethylamine.
Sources & evidence
- ORD record
- ord-81b660289f9d4160af77f53e729367ec
- Source dataset
- uspto-grants-1998_10
- Patent number
- US05817875
Reaction notes
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