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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 399464Generated: October 27, 2026

Sulfabenz → 6,7-dimethoxy-4-[4-(N-phenylsulphamoyl)anilino]quinazoline hydrochloride salt

https://huagongshe.com/reaction/399464

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfabenzHCID 31390—
Reactant4-Chloro-6,7-dimethoxyquinazoline hydrochlorideHCID 22022161—
Product6,7-dimethoxy-4-[4-(N-phenylsulphamoyl)anilino]quinazoline hydrochloride saltHCID 1896762195%

Reaction Steps

Using an analogous procedure to that described in Example 1, 4-amino-N-phenylbenzenesulphonamide was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 6,7-dimethoxy-4-[4-(N-phenylsulphamoyl)anilino]quinazoline hydrochloride salt in 95% yield,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05821246
Source datasetuspto-grants-1998_10
ORD IDord-3d06dbb8567040298524dc7c818aa443
Source noteuspto-grants-1998_10