Pyrithione Sodium → Sodium 1-oxidopyridin-1-ium-2-thiolate

HRID 399542

Reaction equation

HRID 399542 reaction equation
[CH:1]1[CH:7]=[CH:6][N:5]([O-:8])[C:3](=[S:4])[CH:2]=1.[Na+:9]>O>[CH:1]1[CH:7]=[CH:6][N+:5]([O-:8])=[C:3]([SH:4])[CH:2]=1.[CH:1]1[CH:7]=[CH:6][N+:5]([O-:8])=[C:3]([S-:4])[CH:2]=1.[Na+:9].[CH:1]1[CH:7]=[CH:6][N:5]([OH:8])[C:3](=[S:4])[CH:2]=1

Participants

5

Reactant 1

HCID 23685289Pyrithione Sodium

Product 3

HCID 1569Sodium 1-oxidopyridin-1-ium-2-thiolateHCID 1570PyrithioneHCID 178526253HCID 178526253, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Preparation of Comparative Example 2a (chitosan-pyrithione complex): a chitosan slurry was prepared by stirring 1 g VNS-461 into 50 g DI water. A solution of pyrithione acid (PA) was prepared in a separate flask by mixing 2.61 g 40% sodium pyrithione (NaP) solution obtained as sodium Omadine ("Omadine" is a trademark of Olin Corp, Cheshire, Conn.), with 22.4 g DI water and stirring followed by 25.28 g 1% hydrochloric acid. By this method, 99% of the NaP is acidified. The PA solution was added to the chitosan slurry, the mixture stirred 30 minutes, and the chitosan-pyrithione complex was filtered. This process was repeated four more times to yield five filter cakes of chitosan-pyrithione complex.

Workup

  1. customPreparation of Comparative Example 2a (chitosan-pyrithione complex)

Sources & evidence

ORD record
ord-edaab36c719b4daf97c2dfe43e9af4b2
Source dataset
uspto-grants-1998_10
Patent number
US05821271

Linked notes

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