5-Methylnicotinic acid → (4-Iodo-5-methyl-pyridin-3-yl)-carbamic acid tert-butyl ester

HRID 400585

Reaction equation

HRID 400585 reaction equation
[CH3:1]C1C=NC=C(C=1)C(O)=O.[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[CH:19]=[N:20][C:21](C(F)(F)F)=[CH:22][C:23]=1[I:24])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[CH:19]=[N:20][CH:21]=[C:22]([CH3:1])[C:23]=1[I:24])([CH3:12])([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 2562085-Methylnicotinic acidHCID 60026433HCID 60026433, compound

Product 1

HCID 60026355(4-Iodo-5-methyl-pyridin-3-yl)-carbamic acid tert-butyl ester

Procedure

The title product was prepared from 5-methylnicotinic acid in the same manner as in the preparation of (4-iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester.

Sources & evidence

ORD record
ord-38c2a79929724efcab90240367c3c542
Source dataset
uspto-grants-2014_06
Patent number
US08741897B2

Linked notes

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