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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40134Generated: October 23, 2026

Iodocyclopentane → 6-(Cyclopentyloxy)-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide

https://huagongshe.com/en/reaction/40134

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodocyclopentaneHCID 73784—
ReactantHCID 59762291HCID 59762291—
Product6-(Cyclopentyloxy)-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamideHCID 59762323—

Reaction Steps

The title compound was prepared from 6-hydroxy-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide (Compound 141) and cyclopentyl iodide by General Procedure N.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524917B2
Source datasetuspto-grants-2013_09
ORD IDord-3e1a967ccfb44c01b6c2f798819560ee
Source noteuspto-grants-2013_09