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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40141Generated: October 26, 2026

Iodocyclopentane → 6-(Cyclopentyloxy)-N-((5-fluoropyridin-3-yl)methyl)-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamide

https://huagongshe.com/reaction/40141

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodocyclopentaneHCID 73784—
ReactantN-((5-Fluoropyridin-3-yl)methyl)-6-hydroxy-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamideHCID 59762408—
Product6-(Cyclopentyloxy)-N-((5-fluoropyridin-3-yl)methyl)-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamideHCID 59762414—

Reaction Steps

The title compound was prepared from N-((5-fluoropyridin-3-yl)methyl)-6-hydroxy-2-isopropyl-1-(pyridin-3-ylmethyl)-1H-indole-3-carboxamide (Compound 162) and cyclopentyl iodide by General Procedure N.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524917B2
Source datasetuspto-grants-2013_09
ORD IDord-674daa90c9d64af99e844d73d9c31a22
Source noteuspto-grants-2013_09