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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404041Generated: October 26, 2026

4-Pentylbenzoyl chloride → Methyl 2-methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)phenyl)isoindolin-2-yl)propanoate

https://huagongshe.com/reaction/404041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pentylbenzoyl chlorideHCID 170812—
ReactantMethyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-2-methylpropanoateHCID 67307528—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
ProductMethyl 2-methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)phenyl)isoindolin-2-yl)propanoateHCID 6730697793%

Reaction Steps

The compound of example 524 was prepared analogous to compound of example 97 by reaction of compound of example 515 with 4-(n-pentyl)-benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-6051875c64624f378a0b1b19294d922d
Source noteuspto-grants-2014_06