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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404056Generated: October 27, 2026

Methyl 3-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylate → Methyl 3-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylate

https://huagongshe.com/reaction/404056

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylateHCID 67312960—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
ProductMethyl 3-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylateHCID 6731555572%

Reaction Steps

The compound of example 543 was prepared analogous to the compound of example 6 by reduction of the compound of example 542.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-79d7fd5110df4f12ababb2952411bfcf
Source noteuspto-grants-2014_06