Methyl 4-(1,3-oxazol-5-yl)benzoate → (S)-Methyl 3-methyl-2-(6-(4-(4-(oxazol-5-yl)benzamido)phenyl)-1-oxoisoindolin-2-yl)butanoate

Reaction equation

[CH3:1][CH:2]([CH3:38])[C@H:3]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([C:17]3[CH:22]=[CH:21][C:20]([NH:23][C:24](C4SC(C5C=CC=CC=5)=CN=4)=[O:25])=[CH:19][CH:18]=3)=[CH:13][CH:14]=2)[C:9]1=[O:37])[C:4]([O:6][CH3:7])=[O:5].NC1C=CC(C2C=C3C(CN([C@@H](C(C)C)C(OC)=O)C3=O)=CC=2)=CC=1.[O:64]1[C:68]([C:69]2[CH:78]=[CH:77][C:72](C(OC)=O)=[CH:71][CH:70]=2)=[CH:67][N:66]=[CH:65]1>>[CH3:38][CH:2]([CH3:1])[C@H:3]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([C:17]3[CH:18]=[CH:19][C:20]([NH:23][C:24](=[O:25])[C:72]4[CH:71]=[CH:70][C:69]([C:68]5[O:64][CH:65]=[N:66][CH:67]=5)=[CH:78][CH:77]=4)=[CH:21][CH:22]=3)=[CH:13][CH:14]=2)[C:9]1=[O:37])[C:4]([O:6][CH3:7])=[O:5]