HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-chloroaniline → 2,2'-Dichloro-4'-methoxy-[1,1'-biphenyl]-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-chloroaniline | HCID 88888 | — |
| Reactant | 3-Chloro-4-iodoaniline | HCID 282926 | — |
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | 2-Chloro-4-methoxybenzeneboronic acid | HCID 2773330 | — |
| Product | 2,2'-Dichloro-4'-methoxy-[1,1'-biphenyl]-4-amine | HCID 86674296 | — |
Reaction Steps
The title compound was prepared as described in Example 159 substituting 3-chloro-4-iodoaniline and (2-chloro-4-methoxyphenyl)boronic acid for 4-bromo-3-chloroaniline and (4-(trifluoromethyl)phenyl)boronic acid, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748624B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-25b002f29551486d97044d2b393f65ec |
| Source note | uspto-grants-2014_06 |