4-Methoxyphenol → 4-Methoxycyclohexanol (cis,trans)

HRID 406050

Reaction equation

HRID 406050 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[H][H]>C(O)C>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 90154-MethoxyphenolHCID 178418361HCID 178418361, compound

Product 1

HCID 1403324-Methoxycyclohexanol (cis,trans)

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 100 g 4-methoxyphenol and Nishimura's catalyst in 750 ml ethanol were hydrogenated (50 psi hydrogen) at room temperature for 4.5 hours. The mixture was filtered and the filtrate was concentrated.

Workup

  1. customat room temperature
  2. customfor 4.5 hours
  3. filtrationThe mixture was filtered
  4. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-eb53658046a44dc08b8875ac0fe90b71
Source dataset
uspto-grants-2014_06
Patent number
US08754079B2

Linked notes

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