N-(4-Bromophenyl)-2-fluoro-4-methylamino-5-nitro-benzamide → N-(4-bromophenyl)-2-fluoro-4-methylamino-5-amino-benzamide
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:22])[C:10]2[CH:15]=[C:14]([N+:16]([O-])=O)[C:13]([NH:19][CH3:20])=[CH:12][C:11]=2[F:21])=[CH:4][CH:3]=1>[Ni]>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:22])[C:10]2[CH:15]=[C:14]([NH2:16])[C:13]([NH:19][CH3:20])=[CH:12][C:11]=2[F:21])=[CH:6][CH:7]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The subtitle compound is prepared from N-(4-bromophenyl)-2-fluoro-4-methylamino-5-nitro-benzamide, RaNi and H2 in analogy to example 5c.
Sources & evidence
- ORD record
- ord-c050d5d1feea4b8ba5951bd990a05241
- Source dataset
- uspto-grants-2014_06
- Patent number
- US08759537B2
Reaction notes
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