Sodium Azide → 1-Azido-2-(2-methoxyethoxy)ethane

HRID 410980

Reaction equation

Br[CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH3:8].[N-:9]=[N+:10]=[N-:11].[Na+]>>[N:9]([CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH3:8])=[N+:10]=[N-:11]

Participants

Reactant 2

HCID 33557Sodium Azide

HCID 1235321-Bromo-3,6-dioxaheptane

Product 1

HCID 100347511-Azido-2-(2-methoxyethoxy)ethaneYield 76.5%

Procedure

1-Azido-2-(2-methoxy-ethoxy)-ethane (607 mg) was prepared by following General Procedure U starting from 1-bromo-2-(2-methoxy-ethoxy)-ethane (1.0 g) and sodium azide (1.07 g). The crude product was used in the next step without further purification.

Workup

customThe crude product was used in the next step without further purification

Sources & evidence

ORD record: ord-da46aa2df9f94867b4ddaed513066231
Source dataset: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08759535B2

Linked notes

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