4-Phenoxy-2-(4-trifluoromethylphenyl)pyrimidine → 4-(3-Trifluoromethylphenoxy)-2-(4-Trifluoromethylphenyl)-Pyrimidine

HRID 411825

Reaction equation

HRID 411825 reaction equation
C[N:2]1[C:7]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=2)=[CH:6][CH:5]=[N:4][CH:3]1[C:19]1[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][CH:20]=1.O(C1C=CN=C(C2C=CC(C(F)(F)F)=CC=2)N=1)C1C=CC=CC=1>>[F:18][C:15]([F:16])([F:17])[C:11]1[CH:10]=[C:9]([CH:14]=[CH:13][CH:12]=1)[O:8][C:7]1[CH:6]=[CH:5][N:4]=[C:3]([C:19]2[CH:20]=[CH:21][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:23][CH:24]=2)[N:2]=1

Participants

3

Reactant 2

HCID 120568294-Phenoxy-2-(4-trifluoromethylphenyl)pyrimidineHCID 185417023-Methyl-4-(3-trifluoromethylphenoxy)-2-(4-trifluoromethylphenyl)-pyrimidine

Product 1

HCID 99299504-(3-Trifluoromethylphenoxy)-2-(4-Trifluoromethylphenyl)-Pyrimidine

Procedure

Analogously are prepared 3-methyl-4-(3-trifluoromethylphenoxy)-2-(4-trifluoromethylphenyl)-pyrimidine, 5-4-(3-trifluoromethylphenoxy)-2-(4-trifluoromethylphenyl)-pyrimidine, 4-phenoxy-2-(4-trifluoromethylphenyl)pyrimidine

Sources & evidence

ORD record
ord-5eff2ee0a29d4f008aca6314b7e88e89
Source dataset
uspto-grants-2003_05
Patent number
US06559307B2

Linked notes

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