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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412146Generated: October 27, 2026

2-Fluoro-5-methylbenzonitrile → 1-(3-Cyano-4-fluorobenzyl)-5-imidazolecarboxaldehyde

https://huagongshe.com/reaction/412146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-methylbenzonitrileHCID 2774584—
Reactant1-(4-Cyano-3-fluorobenzyl)-5-imidazolecarboxaldehydeHCID 11424708—
Product1-(3-Cyano-4-fluorobenzyl)-5-imidazolecarboxaldehydeHCID 18536066—

Reaction Steps

The titled product was prepared from 3-cyano-4-fluorotoluene using the same procedures as those described in Example 1, Steps D through G for the preparation of 1-(4-cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde, except that 3-cyano-4-fluorotoluene was used in place of 4-cyano-3-fluorotoluene in Step D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562823B1
Source datasetuspto-grants-2003_05
ORD IDord-b86c9e3f6f9c46cda827c3bd970098be
Source noteuspto-grants-2003_05