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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413862Generated: October 25, 2026

Atrolactic acid, (-)- → 5-{N'-((R)-(-)-2-hydroxy-2-phenylpropionyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

https://huagongshe.com/reaction/413862

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAtrolactic acid, (-)-HCID 736858—
Reactant5-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-oneHCID 69736335—
Product5-{N'-((R)-(-)-2-hydroxy-2-phenylpropionyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-oneHCID 86600403—

Reaction Steps

Following one or more of the general procedures outlined above, using (R)-(−)-2-hydroxy-2-phenylpropionic acid and 5-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one, as described in Example 7-B, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: 458 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06569851B1
Source datasetuspto-grants-2003_05
ORD IDord-43ca73deb07e4dde9554a0d3c4fc588b
Source noteuspto-grants-2003_05