HCID 15050550, compound → HCID 59402765, compound

HRID 415622

Reaction equation

HRID 415622 reaction equation
[CH2:1]([C:4]1[CH:13]=[CH:12][C:7]2[N:8]=[C:9](N)[S:10][C:6]=2[CH:5]=1)[CH2:2][CH3:3].C([CH2:16][O:17][C:18]1[C:19]([F:28])=[C:20]([C:25]([NH2:27])=[O:26])[C:21]([F:24])=[CH:22][CH:23]=1)#N>>[F:28][C:19]1[C:18]([O:17][CH2:16][C:9]2[S:10][C:6]3[CH:5]=[C:4]([CH2:1][CH2:2][CH3:3])[CH:13]=[CH:12][C:7]=3[N:8]=2)=[CH:23][CH:22]=[C:21]([F:24])[C:20]=1[C:25]([NH2:27])=[O:26]

Participants

3

Reactant 2

HCID 15050550HCID 15050550, compoundHCID 594028043-(Cyanomethoxy)-2,6-difluorobenzenecarboxamide

Product 1

HCID 59402765HCID 59402765, compoundYield 18%

Procedure

Synthesised from 6-propyl-1,3-benzothiazol-2-amine and 3-(cyanomethoxy)-2,6-difluorobenzenecarboxamide, according to Method K, scheme 26. Yield 18% (second step), mp 173-175° C. HPLC-MS (method 1): m/z 363 [M+H]+, Rt=4.35 min.

Sources & evidence

ORD record
ord-05d3c9817e064d7181bcd88d1db84fca
Source dataset
uspto-grants-2012_01
Patent number
US08088791B2

Linked notes

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