5-Iodo-2-methylbenzaldehyde → 2-methyl-5-(2H-1,2,3-triazol-2-yl)benzaldehyde

Reaction equation

I[C:2]1[CH:3]=[CH:4][C:5]([CH3:10])=[C:6]([CH:9]=1)[CH:7]=[O:8].[NH:11]1[CH:15]=[CH:14][N:13]=[N:12]1>>[CH3:10][C:5]1[CH:4]=[CH:3][C:2]([N:12]2[N:13]=[CH:14][CH:15]=[N:11]2)=[CH:9][C:6]=1[CH:7]=[O:8]

Participants

Reactant 2

HCID 575661265-Iodo-2-methylbenzaldehyde

HCID 178418936HCID 178418936, compound

Product 1

HCID 866724452-methyl-5-(2H-1,2,3-triazol-2-yl)benzaldehyde

Procedure

The title compound was synthesized in analogy to the procedure described for building block K49 from 5-iodo-2-methylbenzaldehyde [65874-26-2] and 1H-1,2,3-triazole.

Sources & evidence

ORD record: ord-e818e93ca66749d985b560a99c20149c
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08530648B2

Reaction notes

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