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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 41802Generated: October 26, 2026

2-Oxoglutaric Acid → 1,4,5,6-Tetrahydro-6-oxo-3-pyridazinecarboxylic acid

https://huagongshe.com/reaction/41802

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxoglutaric AcidHCID 51—
ReactantHydrazineHCID 9321—
Product1,4,5,6-Tetrahydro-6-oxo-3-pyridazinecarboxylic acidHCID 9962199%

Reaction Steps

The disclosed embodiments stem from the examination of several classes of compounds that quantitatively react with hydrazine to form stable organic products. The reaction of 2-ketoglutaric acid with hydrazine reacts to provide a greater than 99% yield of 6-oxo-1,4,5,6-tetrahydro-pyridazine-3-carboxylic acid (PCA) based on hydrazine as the limiting reagent. It has been found that this compound allows for the facile remediation of hydrazine under a variety of conditions. The focus of the disclosed embodiments concerns the use of 2-ketoglutaric acid or other dicarbonyl compounds for the remediation of hydrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08535430B2
Source datasetuspto-grants-2013_09
ORD IDord-e3234c6d563d46798823285107d150ba
Source noteuspto-grants-2013_09