2,5-Dimethyl-1H-indole → 8-Bromo-4-(2,5-dimethyl-1H-indol-3-yl)-2-methylquinoline, hydrochloride

HRID 418435

Reaction equation

HRID 418435 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2.[Br:12][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]2[C:22]=1[N:21]=[C:20]([CH3:23])[CH:19]=[C:18]2[Cl:24]>>[ClH:24].[Br:12][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]2[C:22]=1[N:21]=[C:20]([CH3:23])[CH:19]=[C:18]2[C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH3:11])[CH:8]=2)[NH:3][C:2]=1[CH3:1]

Participants

3

Reactant 2

HCID 709652,5-Dimethyl-1H-indoleHCID 7684838-Bromo-4-chloro-2-methylquinoline

Product 1

HCID 1317293498-Bromo-4-(2,5-dimethyl-1H-indol-3-yl)-2-methylquinoline, hydrochloride

Procedure

The sub-title compound was prepared by the method of Example 15 step a, using 2,5-dimethylindole and 8-bromo-4-chloro-2-methylquinoline.

Sources & evidence

ORD record
ord-e94adc7c3c0d4bfea4150d3d7060d515
Source dataset
uspto-grants-2012_01
Patent number
US08093278B2

Linked notes

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