2,5-Dimethyl-1H-indole → 4-(2,5-Dimethyl-1H-indol-3-yl)-8-methoxy-2-methylquinoline, hydrochloride

HRID 418436

Reaction equation

HRID 418436 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2.[Cl:12][C:13]1[C:22]2[C:17](=[C:18]([O:23][CH3:24])[CH:19]=[CH:20][CH:21]=2)[N:16]=[C:15]([CH3:25])[CH:14]=1>>[ClH:12].[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[C:13]1[C:22]3[C:17](=[C:18]([O:23][CH3:24])[CH:19]=[CH:20][CH:21]=3)[N:16]=[C:15]([CH3:25])[CH:14]=1)=[CH:8][C:7]([CH3:11])=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 709652,5-Dimethyl-1H-indoleHCID 8075834-Chloro-8-methoxy-2-methylquinoline

Product 1

HCID 1317293504-(2,5-Dimethyl-1H-indol-3-yl)-8-methoxy-2-methylquinoline, hydrochloride

Procedure

The sub-title compound was prepared by the method of Example 15 step a), using 2,5-dimethylindole and 4-chloro-8-methoxy-2-methylquinoline.

Sources & evidence

ORD record
ord-fb74a4a066fa4600b7bf626815325674
Source dataset
uspto-grants-2012_01
Patent number
US08093278B2

Linked notes

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