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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42015Generated: October 25, 2026

2,5-Dibromo-3-methylpyridine → 5-Bromo-2-(3-ethoxyphenyl)-3-methylpyridine

https://huagongshe.com/reaction/42015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dibromo-3-methylpyridineHCID 817680—
Reactant3-Ethoxybenzeneboronic acidHCID 2773920—
Product5-Bromo-2-(3-ethoxyphenyl)-3-methylpyridineHCID 5841576037%

Reaction Steps

Obtained (1.30 g, yield 37%) following the procedure described in Intermediate 27, starting with 2,5-dibromo-3-methylpyridine (11.96 mmol, 3.0 g), 3-ethoxyphenylboronic acid (11.96 mmol, 1.98 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536165B2
Source datasetuspto-grants-2013_09
ORD IDord-33a4b93db77a4bf6a6afdfbf2888e006
Source noteuspto-grants-2013_09