HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → Methyl 2-(bromomethyl)-3-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | Succinimide | HCID 11439 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 2-methyl-3-nitrobenzoate | HCID 601165 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 2-(bromomethyl)-3-nitrobenzoate | HCID 1487795 | — |
Reaction Steps
25.55 g (130.9 mmol) of 2-methyl-3-nitrobenzoic acid methyl ester is added to 300 ml of carbon tetrachloride, and mixed with 25.6 g (141.7 mmol) of N-bromosuccinimide and 62.8 mg of benzoyl peroxide. After seven days of refluxing, the succinimide is suctioned off after cooling, and then the filtrate is spun in until a dry state is reached. The desired compound that is incorporated in crude form into the next stage remains.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097627B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-bac3f96a75ac43479751c769eee1363d |
| Source note | uspto-grants-2012_01 |