5-Chlorosalicylic Acid → 5-Chloro-N-(6-chloro-4-methoxypyrimidin-2-yl)-2-hydroxybenzamide

HRID 421035

Reaction equation

HRID 421035 reaction equation
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[N:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([Cl:21])[N:14]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[N:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([Cl:21])[N:14]=1)=[O:9]

Participants

3

Reactant 2

HCID 94475-Chlorosalicylic AcidHCID 798112-Pyrimidinamine, 4-chloro-6-methoxy-

Product 1

HCID 99729035-Chloro-N-(6-chloro-4-methoxypyrimidin-2-yl)-2-hydroxybenzamideYield 2.2%

Procedure

Using 5-chlorosalicylic acid and 2-amino-6-chloro-4-methoxypyrimidine as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-1b67804c6d4a422a8157104ecd4213cb
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Linked notes

Loading…