Sodium Hydroxide → HCID 66673266, compound

HRID 421541

Reaction equation

HRID 421541 reaction equation
[OH-].[Na+].[C:3]([NH:6][C:7](=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:8]([OH:10])=[O:9])(=[O:5])[CH3:4].[Cl-].[Zn+2:19].[Cl-]>O>[C:3]([NH:6][C:7](=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:8]([O-:10])=[O:9])(=[O:5])[CH3:4].[Zn+2:19].[C:3]([NH:6][C:7](=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:8]([O-:10])=[O:9])(=[O:5])[CH3:4]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 956312-(Acetylamino)-3-phenyl-2-propenoic acidHCID 3007855Zincchloride

Product 1

HCID 66673266HCID 66673266, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Conditions

Temperature
70 °C

Procedure

A solution of 47% (w/w) sodium hydroxide (5.5 g) is added to slurry of α-acetamidocinnamic acid (10.3 g, 0.05 mol) in water (100 mL) at 70° C. to give a clear slightly alkaline solution. A solution of zinc chloride (3.4 g, 0.025 mol) in water (50 mL) is added and a precipitate is formed immediately. The mixture is stirred at 70° C. for further 2.5 hours. The precipitate is then filtered and dried to yield 9.4 g (80%) zinc α-acetamidocinnamate as a fine white powder. IR absorption bands: 1560, 1510, 1402 and 1353 cm−1.

Workup

  1. customto give a clear slightly alkaline solution
  2. customa precipitate is formed immediately
  3. filtrationThe precipitate is then filtered
  4. customdried

Sources & evidence

ORD record
ord-b85fbb8e1f5e4d1586c1a4d8a9f68b15
Source dataset
uspto-grants-2012_01
Patent number
US08101544B2

Linked notes

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