Sodium Carbonate → Sodium carbonate bicarbonate

Reaction equation

CC(OCC1CS[C@@H]2[C@H](NC(CCC[C@@H](N)C(O)=O)=O)C(=O)N2C=1C(O)=O)=O.[C:29](=[O:32])([O-:31])[O-:30].[Na+:33].[Na+]>>[C:29](=[O:30])([O-:32])[O-:31].[Na+:33].[Na+:33].[C:29](=[O:30])([OH:32])[O-:31]

Participants

Reactant 2

HCID 10340Sodium Carbonate

HCID 65536Cephalosporin C

Product 1

HCID 86624777Sodium carbonate bicarbonate

Procedure

Separately, 20 ml of a solution containing 119.8 mg of cephalosporin-C and 54 mg of sulphosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate (sSMCC, 22322 Pierce) in sodium carbonate buffer (100 mM, pH 9) are incubated for one hour at 25° C.

Sources & evidence

ORD record: ord-6e9f901bf38a48ff867e24002c03eeed
Source dataset: uspto-grants-2012_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08106155B2

Reaction notes

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