HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 66703605, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Fluoro-4-(trifluoromethyl)benzoyl chloride | HCID 145580 | — |
| Reactant | 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one | HCID 33699394 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 66703605 | HCID 66703605 | — |
Reaction Steps
2-Fluoro-4-(trifluoromethyl)benzoyl chloride was added to a pyridine solution of 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one, followed by stirring at room temperature for 12 hours. Water was added to the reaction liquid, followed by stirring for 30 minutes and then the precipitated crystals were collected by filtration to obtain 2-fluoro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(trifluoromethyl)benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106190B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-37e90418f05547b9ae14e3e6437759f8 |
| Source note | uspto-grants-2012_01 |