1-Chloro-2-fluoro-3-nitrobenzene → Ethyl 2-(2-chloro-6-nitroanilino)-5-ethyl-thiophene-3-carboxylate

HRID 427028

Reaction equation

HRID 427028 reaction equation
[NH2:1][C:2]1[S:3][C:4]([CH2:12][CH3:13])=[CH:5][C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].[Cl:14][C:15]1[C:16](F)=[C:17]([N+:21]([O-:23])=[O:22])[CH:18]=[CH:19][CH:20]=1>CCO>[Cl:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[C:16]=1[NH:1][C:2]1[S:3][C:4]([CH2:12][CH3:13])=[CH:5][C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Participants

4

Reactant 2

HCID 750161-Chloro-2-fluoro-3-nitrobenzeneHCID 78263Ethyl 2-amino-5-ethyl-3-thenoate

Product 1

HCID 20387682Ethyl 2-(2-chloro-6-nitroanilino)-5-ethyl-thiophene-3-carboxylate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 2-amino-5-ethyl-thiophene-3-carboxylate and 3-chloro-2-fluoronitrobenzene, m.p. 67°-70° C. (EtOH).

Sources & evidence

ORD record
ord-cdbd6dbddb8f4136a2d630e4a039e40d
Source dataset
uspto-grants-1979_10
Patent number
US04172831

Linked notes

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