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2-Ethyl-5-phenyl-oxazole-4-carboxylic acid → 2-Ethyl-5-phenyl-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

HRID 42908
Notes
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Reaction equation

HRID 42908 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[N:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[CH2:19]([C:21]1[O:22][C:23]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[C:24]([C:26](O)=[O:27])[N:25]=1)[CH3:20]>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[N:17]=[C:16]([NH:18][C:26]([C:24]3[N:25]=[C:21]([CH2:19][CH3:20])[O:22][C:23]=3[C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)=[O:27])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 669290412-Ethyl-5-phenyl-oxazole-4-carboxylic acidHCID 673642472-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 426462742-Ethyl-5-phenyl-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

Procedure

Following general procedure A followed by L, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 2-ethyl-5-phenyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-e57df55d3814414380347ba70b7079e4
Source dataset
uspto-grants-2013_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US08536209B2

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes