5-Phenyl-1,3-oxazole-4-carboxylic acid → 5-Phenyl-oxazole-4-carboxylic acid [2-(5,5-difluoro-hexyl)-2H-[1,2,3]triazol-4-yl]-amide

HRID 42915

Reaction equation

HRID 42915 reaction equation
[F:1][C:2]([F:14])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[N:11]=[C:10]([NH2:12])[CH:9]=[N:8]1.[C:15]1([C:21]2[O:25][CH:24]=[N:23][C:22]=2[C:26](O)=[O:27])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[F:14][C:2]([F:1])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[N:11]=[C:10]([NH:12][C:26]([C:22]2[N:23]=[CH:24][O:25][C:21]=2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[O:27])[CH:9]=[N:8]1

Participants

3

Reactant 2

HCID 27762995-Phenyl-1,3-oxazole-4-carboxylic acidHCID 67365266HCID 67365266, compound

Product 1

HCID 426465215-Phenyl-oxazole-4-carboxylic acid [2-(5,5-difluoro-hexyl)-2H-[1,2,3]triazol-4-yl]-amide

Procedure

Following general procedure A, starting from 2-(5,5-difluoro-hexyl)-2H-[1,2,3]triazol-4-ylamine and 5-phenyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-ed9c74fcdb964d01a4555b1200ec1d23
Source dataset
uspto-grants-2013_09
Patent number
US08536209B2

Linked notes

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