2-Hydrazinopyridine → 7H-Pyrrolo(2,3-d)pyrimidine

HRID 429189

Reaction equation

HRID 429189 reaction equation
[NH:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1)N.[NH:9]([C:11]1[N:12]=[N:13][CH:14]=[CH:15][CH:16]=1)N.[NH:17]([C:19]1[CH:24]=N[CH:22]=[CH:21][N:20]=1)[NH2:18]>>[N:4]1[C:3]2[NH:1][CH:6]=[CH:7][C:8]=2[CH:11]=[N:9][CH:5]=1.[N:17]1[C:19]2[NH:20][CH:21]=[CH:22][C:24]=2[CH:16]=[CH:11][N:18]=1.[N:1]1[CH:3]=[CH:8][N:12]=[C:11]2[NH:13][CH:14]=[CH:15][C:16]=12

Participants

6

Reactant 3

HCID 786452-HydrazinopyridineHCID 14878232-HydrazinopyrazineHCID 122953913-Hydrazinopyridazine

Product 3

HCID 2615917H-Pyrrolo(2,3-d)pyrimidineHCID 53708035H-Pyrrolo[2,3-b]pyrazineHCID 115137407H-Pyrrolo(2,3-c)pyridazine

Procedure

Substituting 2-hydrazinopyridine 51 with 4-hydrazinopyrimnidine, 3-hydrazinopyridazine or 2-hydrazinopyrazine and following the procedure described above gives 7H-pyrrolo[2,3-d]pyrimidine, 7H-pyrrolo[2,3-c]pyridazine or 5H-pyrrolo[2,3-b]pyrazine respectively.

Sources & evidence

ORD record
ord-5081b819a45a45629defd57feecc2dce
Source dataset
uspto-grants-2001_11
Patent number
US06316464B1

Linked notes

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