Acetic Acid → 2-Dodecylsulfonyl-4-chloronitrobenzene

HRID 429504

Reaction equation

HRID 429504 reaction equation
C(O)(=O)C.[CH2:5]([S:17][C:18]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=1[N+:25]([O-:27])=[O:26])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH2:28].[OH:29]O>[W].O>[CH2:5]([S:17]([C:18]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=1[N+:25]([O-:27])=[O:26])(=[O:29])=[O:28])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

6

Reactant 3

HCID 176Acetic AcidHCID 449047Hydrogen peroxide waterHCID 183562912-n-Dodecylthio-4-chloronitrobenzene

Product 1

HCID 183562922-Dodecylsulfonyl-4-chloronitrobenzene

Reagents, catalysts & solvents 2

HCID 23964TungstenCatalystHCID 962WaterSolvent

Procedure

0.2 g of tungsten acid sodium salt (II) hydrate was added to 40 ml of an acetic acid solution in which 17.9 g of 2-n-dodecylthio-4 -chloronitrobenzene was mixed, and 12.5 g of a 30% hydrogen peroxide water was added dropwise at an internal temperature of 70° C, and a reaction was carried out at that same temperature over three hours. The reaction solution was cooled to room temperature, and 120 ml of water was added. The precipitated crystals were filtered, washed with water and dried, and 19.5 g of 2-n-dodecylsulfonyl-4-chloronitrobenzene was obtained as a slightly yellow crystal.

Workup

  1. additionwas mixed
  2. filtrationThe precipitated crystals were filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-0447122ceec141118859f5e49abee20f
Source dataset
uspto-grants-2001_11
Patent number
US06316605B1

Linked notes

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