HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(4-Methylpiperazin-1-yl)pyridin-3-amine → 8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(4-Methylpiperazin-1-yl)pyridin-3-amine | HCID 2763390 | — |
| Reactant | 8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [4-(4-methyl-piperazin-1-yl)phenyl]-amide | HCID 44515355 | — |
| Product | 8-Naphthalen-1-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]amide | HCID 59292934 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described in Step 14.1 but stirring the reaction mixture for 20 h at it and using 6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine (prepared as described in Example 33 but using N-methyl-piperazine in Step 33.2) and 8-naphthalen-1-yl-quinoxaline-5-carboxylic acid (Example 46). Title compound: ESI-MS: 475.0 [M+H]+; tR=3.76 min (System 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536175B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-2f03f2f53ea845e79c20cecc01c56688 |
| Source note | uspto-grants-2013_09 |