4-[2-(Dimethylamino)ethoxy]aniline → HCID 59292826, compound

HRID 43093

Reaction equation

HRID 43093 reaction equation
[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1.C(N1CCN(C2C=C(N[C:29]([C:31]3[C:32]4[N:33]=[CH:34][CH:35]=[N:36][C:37]=4[C:38]([C:41]4[CH:46]=[C:45]([O:47][CH3:48])[CH:44]=[CH:43][C:42]=4[Cl:49])=[CH:39][CH:40]=3)=[O:30])C=CC=2)CC1)C>>[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:29]([C:31]2[C:32]3[N:33]=[CH:34][CH:35]=[N:36][C:37]=3[C:38]([C:41]3[CH:46]=[C:45]([O:47][CH3:48])[CH:44]=[CH:43][C:42]=3[Cl:49])=[CH:39][CH:40]=2)=[O:30])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 64846554-[2-(Dimethylamino)ethoxy]anilineHCID 445159808-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amide

Product 1

HCID 59292826HCID 59292826, compound

Procedure

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(2-dimethylamino-ethoxy)-phenylamine (Step 5.1) and 8-(2-chloro-5-methoxyphenyl)-quinoxaline-5-carboxylic acid (Example 63). Title compound: ESI-MS: 476.9 [M]+; tR=3.43 min (System 3).

Workup

  1. customThe title compound was prepared in analogy to the procedure

Sources & evidence

ORD record
ord-03aed7d711e943508c90ed0abc9aad80
Source dataset
uspto-grants-2013_09
Patent number
US08536175B2

Linked notes

Loading…