4-Chloroaniline → Benzamide, N-(4-chlorophenyl)-2-hydroxy-

HRID 433026

Reaction equation

HRID 433026 reaction equation
[C:1]([O:10]C1C=CC=CC=1)(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[Cl:17][C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:24]=[CH:23][C:21]([NH:22][C:1](=[O:10])[C:2]2[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=2)[OH:4])=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 78124-ChloroanilineHCID 8361Phenyl Salicylate

Product 1

HCID 77253Benzamide, N-(4-chlorophenyl)-2-hydroxy-

Procedure

The 4′-chloro-salicylanilide was prepared by condensing phenyl salicylate with 4-chloroaniline then purified as described in Example 2a.

Workup

  1. customthen purified

Sources & evidence

ORD record
ord-4c0452b41ce8498b98b79726f18538cf
Source dataset
uspto-grants-2003_12
Patent number
US06664427B1

Linked notes

Loading…