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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43345Generated: October 25, 2026

tert-Butyl 4-oxopiperidine-1-carboxylate → 1,1-Dimethylethyl 4-{[4-fluoro-3-(methyloxy)phenyl]amino}-1-piperidinecarboxylate

https://huagongshe.com/reaction/43345

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant4-Fluoro-3-methoxyanilineHCID 2774533—
Reactanttert-Butyl 4-(4-fluoroanilino)piperidine-1-carboxylateHCID 16413902—
Product1,1-Dimethylethyl 4-{[4-fluoro-3-(methyloxy)phenyl]amino}-1-piperidinecarboxylateHCID 57699524—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-oxo-1-piperidinecarboxylate and 4-fluoro-3-methoxyaniline using a method similar to that described for D1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536182B2
Source datasetuspto-grants-2013_09
ORD IDord-2bf0537e4add40a7bc33873b1154f9a7
Source noteuspto-grants-2013_09