Ethyl orthoformate → 4-Chloro[1,2,4]triazolo[4,3-a]quinoxaline

Participants

Reaction Steps

A 10 g. portion of 2-chloro-3-hydrazinoquinoxaline was added to 200 ml. of triethylorthoformate and the mixture was rapidly heated to reflux temperature. After 1 hour of heating, with constant stirring, the reaction mixture was cooled and 10.6 g. of product was collected by filtration. The product was identified as 4-chloro-s-triazolo[ 4,3-a]-quinoxaline, m.p. 285°-86° C., by nuclear magnetic resonance analysis and by elemental microanalysis, the results of which follow.

Provenance & Evidence