Ethyl isothiocyanate → 1-[4-(2-Acetylhydrazino)phenyl]-3-ethylthiourea

HRID 437290

Reaction equation

[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)(=[O:3])[CH3:2].[CH2:13]([N:15]=[C:16]=[S:17])[CH3:14]>>[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:16]([NH:15][CH2:13][CH3:14])=[S:17])=[CH:8][CH:7]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 10966Ethyl isothiocyanate

HCID 81068Acetic acid, 2-(4-aminophenyl)hydrazide

Product 1

HCID 214278201-[4-(2-Acetylhydrazino)phenyl]-3-ethylthiourea

Procedure

1-Acetyl-2-(4-aminophenyl)hydrazine (1.65 g, 0.01 mole) and ethyl isothiocyanate (0.87 g, 0.01 mole) were reacted according to procedure (11.). Yield 1.7 g (67%), p.m. 191°-193° C.

Workup

custom191°-193° C.

Sources & evidence

ORD record: ord-def1e4d478ff4be69fd2de3d3049637f
Source dataset: uspto-grants-1977_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04030925

Linked notes

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