1-Benzyl-4-(o-tolyloxy)piperidine → 4-(2-Methylphenoxy)piperidine
Reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[CH3:21])[CH2:10][CH2:9]1)C1C=CC=CC=1>C(O)C>[C:16]1([CH3:21])[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[O:14][CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
By following the manipulative procedure described in Example 1(b), a solution of 8.3 g of 1-benzyl-4-(o-tolyloxy)piperidine in 100 ml. of ethanol produces a colorless oil of 4-(o-tolyloxy)piperidine.
Sources & evidence
- ORD record
- ord-885ea744b77b469885b0be60f2d3d672
- Source dataset
- uspto-grants-1977_06
- Patent number
- US04031221
Reaction notes
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