Bis(3-aminopropyl)amine → N,N-Bis-[3-(3,4-dihydro-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-amine

Participants

Reaction Steps

N,N-Bis-[3-(3,4-dihydro-1,3-dioxo-2(1H)-isoquinolyl)-propyl]-amine was prepared analogous to Example 30 from 2.44 gm of isochroman-1,3-dione and N,N-bis-(3-amino-propyl)-amine. The hydrochloride was precipitated from acetone with ethereal hydrochloric acid. M.p. of the hydrochloride: 135° -140° C; yield: 0.17 gm (2.5% of the theory).

Provenance & Evidence