Isonicotinamidine → 2-(Pyridin-2-yl)pyrimidin-4-amine

HRID 437761

Reaction equation

HRID 437761 reaction equation
C(N)(=N)[C:2]1C=C[N:5]=[CH:4][CH:3]=1.[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]([NH2:18])=[NH:17]>>[NH2:5][C:4]1[CH:3]=[CH:2][N:18]=[C:16]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][N:10]=2)[N:17]=1

Participants

3

Reactant 2

HCID 409094IsonicotinamidineHCID 556504Picolinimidamide

Product 1

HCID 124036162-(Pyridin-2-yl)pyrimidin-4-amine

Procedure

Following the procedure described in Example A-1 but using in place of isonicotinamidine a molar equivalent quantity of the appropriate pyridine carboxamidine, i.e., Q-C(=NH)NH2, the 4-amino-2-Q-pyrimidines of Examples A-10 through A-13 are obtained:

Sources & evidence

ORD record
ord-ace7c523d8664aaf9db66e582ce975a7
Source dataset
uspto-grants-1977_06
Patent number
US04032523

Linked notes

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