Ethyl 2-Formylpropionate → HCID 23334400, compound

HRID 437958

Reaction equation

HRID 437958 reaction equation
C(O[C:4](=[O:9])[CH:5]([CH:7]=O)[CH3:6])C.[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH2:14][NH:15][NH2:16]>C(O)C>[CH3:6][C:5]1[C:4](=[O:9])[N:15]([CH2:14][C:13]2[CH:17]=[CH:18][C:19]([Cl:20])=[C:11]([Cl:10])[CH:12]=2)[NH:16][CH:7]=1

Participants

4

Reactant 2

HCID 10898741Ethyl 2-FormylpropionateHCID 20495842HCID 20495842, compound

Product 1

HCID 23334400HCID 23334400, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 7.5 g of α-formylpropionic acid ethyl ester in 50 ml ethanol were added dropwise 10.9 g 3,4-dichlorobenzylhydrazine. After stirring overnight at room temperature, the solvent was distilled off in a vacuum and the solid residue was recrystallized from ethanol. m.p. 156° C., 9.3 g (64% of theory).

Workup

  1. distillationthe solvent was distilled off in a vacuum
  2. customthe solid residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-9088c4aaa69245df9c404df7496e1be9
Source dataset
uspto-grants-1977_06
Patent number
US04032646

Linked notes

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