HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-(2,3,4,5,6-pentahydroxy-hexyl)-L-(+)-citrulline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Citrulline | HCID 9750 | — |
| Reactant | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| Catalyst | Nickel | HCID 935 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(2,3,4,5,6-pentahydroxy-hexyl)-L-(+)-citrulline | HCID 53994813 | — |
Reaction Steps
The product was made from D-glucose and L-(+)-citrulline using Raney nickel or palladium/activated carbon as a catalyst and heating for 2 hours to 50° C. and 4 hours to 70° C. A product was obtained which had a melting point of 176° C. and an RF -value of 0.7 (determined on DC-finished plates of silica gel G (Merck) with a transporting liquid made up of 50 parts by volume of methanol and 50 parts by volume of water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032676 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-472cad92d8bf42c8b51cc60e4936cd3f |
| Source note | uspto-grants-1977_06 |