4-Bromo-3-chloro-3,4,4-trifluorobutanoic acid → 3,4,4-Trifluoro-3-butenoic acid
Reaction equation
Br[C:2]([F:11])([F:10])[C:3](Cl)([F:8])[CH2:4][C:5]([OH:7])=[O:6]>[Zn]>[F:8][C:3](=[C:2]([F:11])[F:10])[CH2:4][C:5]([OH:7])=[O:6]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Dehalogenation of 4-bromo-3-chloro-3,4,4-trifluorobutanoic acid (VIII) with zinc using conditions analogous to those disclosed in the literature to obtain the desired 3,4,4-trifluoro-3-butenoic acid (IV); or
Sources & evidence
- ORD record
- ord-de96e68cb5a44b66b1b2ca98cca9f270
- Source dataset
- uspto-grants-1996_05
- Patent number
- US05514717
Reaction notes
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