Glycine → Alanine serine

Reaction equation

[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3].[NH2:7][CH2:8][C:9]([OH:11])=[O:10]>>[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3].[NH2:7][C@H:8]([C:9]([OH:11])=[O:10])[CH2:4][OH:5]

Participants

Reactant 2

HCID 750Glycine

HCID 5950L-Alanine

Product 1

HCID 87220707Alanine serine

Procedure

The formation of Z--Ala--SerOH is obtained by the same process as that described in Example 1.a, but using 1.1 mmol of lyophilised hydrated serine in place of cysteine and 1 mmol of alanine protected by Z and activated in place of glycine.

Sources & evidence

ORD record: ord-d3765d8579c44d02900e70b0d80879d8
Source dataset: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04725645

Reaction notes

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