Fenoprofen → Fenoprofen Sodium

HRID 442230

Reaction equation

HRID 442230 reaction equation
C(=O)([O-])[O-].[Na+:5].[Na+].[O:7]([C:14]1[CH:15]=[C:16]([CH:20]([CH3:24])[C:21]([OH:23])=[O:22])[CH:17]=[CH:18][CH:19]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>O>[O:7]([C:14]1[CH:15]=[C:16]([CH:20]([CH3:24])[C:21]([O-:23])=[O:22])[CH:17]=[CH:18][CH:19]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1.[Na+:5]

Participants

4

Reactant 2

HCID 3342FenoprofenHCID 10340Sodium Carbonate

Product 1

HCID 23666712Fenoprofen Sodium

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In a suitable vessel, 32.8 g. of anhydrous sodium carbonate were dissolved in 500 ml. of deionized water. To this solution were added 100 g of 2-(3-phenoxyphenyl)propionic acid. The reaction mixture was agitated vigorously until all of the acid was in solution and reacted to form sodium 2-(3-phenoxyphenyl)propionate. The resulting reaction mixture was diluted to a total volume of 2 l with deionized water. The dilute propionate solution was transferred to a 4 liter beaker.

Workup

  1. customreacted

Sources & evidence

ORD record
ord-fad5f21beaad437eb232c47884234ac5
Source dataset
uspto-grants-1977_08
Patent number
US04044149

Linked notes

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