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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442483Generated: October 27, 2026

2-Chloro-N-(4-methylphenyl)acetamide → 4-p-Methylanilinocarbonylmethylamino-1-(4-phenyl-4-oxobutyl) piperidine

https://huagongshe.com/reaction/442483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-N-(4-methylphenyl)acetamideHCID 27967—
Reactant4-Amino-1-(4-phenyl-4-oxobutyl)piperidineHCID 12608537—
Product4-p-Methylanilinocarbonylmethylamino-1-(4-phenyl-4-oxobutyl) piperidineHCID 54474776—

Reaction Steps

Using a procedure analogous to Example 1 4-amino-1-(4-phenyl-4-oxobutyl) piperidine may be reacted with N-(p-tolyl) chloro-acetamide to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04045566
Source datasetuspto-grants-1977_08
ORD IDord-06c24b2136434725bd3aa472040ca60e
Source noteuspto-grants-1977_08